Clinical and epidemiological characteristics of chronic leukemias in a cohort from the Central Military Hospital

Introduction: Chronic leukemias, including chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL), represent a significant challenge in hematologic oncology. While these diseases have been extensively studied in European and North American populations, data in Mexico remain limited. This study describes the demographic, clinical, and survival characteristics of patients with CML and CLL treated at the Central Military Hospital over a 25-year period. Objective: This study aims to fill this gap in knowledge by describing the demographic and clinical characteristics of patients with CML and CLL treated at this high-specialty institution. Material and method: A retrospective, observational, and descriptive study was conducted based on the clinical records of 153 patients with confirmed diagnosis of CML (n = 85) and CLL (n = 68). Variables such as age, sex, place of residence, and overall survival (OS) were analyzed using the Kaplan-Meier method. Results: The median age at diagnosis was 43 years for CML and 67 years for CLL. Most patients were from the State of Mexico (30.9%) and Mexico City (20.6%). The 15-year OS was 90.8% for CLL and 87.5% for CML. Conclusion: This study highlights key differences in the epidemiology and progression of chronic leukemias in Mexico, providing valuable information for resource planning and healthcare strategies.